The architecture of tumors plays an important role in tumor development. The understanding of these structures and the forces that drive their formation is of high importance in cancer research and therapy. We develop quantitative experimental-theoretical methods to provide an in-depth understanding of the influence of the cell-cell and cell-environment interactions on directed cell-cell movement, cellular signaling and cancer tissues architectures.

Our studies encompass analytical approaches from physics and chemistry, molecular profiling and analysis of tumor tissues, single cell measurements and live cell imaging of 2D and 3D cell cultures.